Structured Drug Safety Knowledge Base
Normalized side effects with frequency and severity. Interactions with mechanism, outcome symptoms, source, and a versioned KB stamp.
For clinics, physicians & care teams
Astra Sentinel gives your patients a structured way to journal symptoms, medications, and labs — and gives you a deterministic Drug–Drug Interaction engine with explanations, mechanisms, and a full audit trail.

"New onset confusion, 4 days after starting tramadol."
Likely culprit · Tramadol + Sertraline
Mechanism: serotonergic synergy · Score 78 · Severity: high
Lab modifier · Creatinine 1.8
+15 — reduced clearance of renally-excreted meds
Escalation: contact prescriber
Engine v1 · KB v2026.05
Why this matters
A symptom appears Tuesday. A new prescription started the Thursday before. A creatinine quietly drifted up last month. Three signals, three different systems, one patient — and the chart visit is in fifteen minutes. Astra is the connective tissue.
What you get
Normalized side effects with frequency and severity. Interactions with mechanism, outcome symptoms, source, and a versioned KB stamp.
Five rules — single-med match, interaction match, timing alignment, lab modifiers, red-flag escalation — produce a ranked, explainable list of candidates.
See only what your patient explicitly shares: symptom timeline, medication history with dose & start dates, and a fixed lab panel.
Every analysis is logged: inputs, outputs, KB version, engine version, escalation tier. Compliance-ready from day one.
How it works for clinicians
01
Your patient generates a secure access code. You enter it once — access expires in 90 days unless renewed.
02
Their symptoms, medications, labs, and journals laid out chronologically. Nothing they didn't choose to share.
03
Before prescribing, run a real-time check against everything they're already on. See mechanism, score, and severity in one screen.
Patient stories shared with the community show shape, not identity.
Chest pain, anaphylaxis, trouble breathing — surfaced with a "contact now" tier.
Astra augments your judgment. It does not replace a clinical exam.
Free for the pilot. Set up in under five minutes. We'll help you onboard your first three patients.
Request clinic access